徐彤 教授、博士

徐彤.jpg

徐彤:男,生于1969年,河北省滦平县人,博士、二级教授,硕士生导师。主要从事动物传染病教学与科研工作,尤其是动物流感病毒致哺乳动物肺损伤机理的相关科研工作。到目前为止,主持和参与国家自然基金、河北省自然基金、河北省科技攻关、河北省教育厅和张家口市科技攻关等科研课题十余项。获河北省科技进步三等奖,河北省山区创业三等奖以及张家口市科技进步一等奖、二等奖各1项。在Am. J. Respir. Crit. Care Med、European Respiratory Journal、Journal of General Virology、Respiratory research、Int Immunopharmacol、 Acta Virologic、畜牧兽医学报、中国病理生理杂志、预防兽医学报等国内外刊物发表论文120余篇,SCI收录30篇。其中以第一作者在国际呼吸领域著名刊物美国呼吸与重症监护医学和欧洲呼吸杂志上发表题为“Acute Respiratory Distress Syndrome Induced by Avian Influenza A (H5N1) Virus in Mice(2006年)”和 “Effect of dexamethasone on acute respiratory distress syndrome induced by the H5N1 virus in mice(2009年)”,当年影响因子分别达到9.07和5.549。

现为国家自然基金、河北省自然基金和河北省山区创业奖评审专家;国家科技部、北京市、重庆市、黑龙江省和江西省等科技项目评审入库专家;河北省第二、三期(2018年-2022年)现代化产业体系肉鸡疫病防控岗位专家;现为河北省畜牧兽医学会副理事长、河北省蛋禽、肉鸡学会副理事长,河北省动物疫情解析预警专家。

以第一作者或通讯作者发表部分论文

[1] Xu T, Qiao J, Zhao LH, Wang GR, He GM, Li K, Tian Y, Gao MJ, Wang JL,Wang HY, Dong CG. Acute Respiratory Distress Syndrome Induced by Avian Influenza A (H5N1) Virus in Mice. Am. J. Respir. Crit. Care Med, 2006, 174: 1011-1017( IF=9.07)

[2] Xu T, Qiao J, Zhao LH, He GM, Li K, Wang JL, Tian Y, Wang HY. The Effect of Dexmethine on Acute Respiratory Distress Syndrome Induced by Avian Influenza A (H5N1) Virus in Mice. Eur Respir J. 2009 ;33(4):852-60 ( IF=5.45)

[3] Tong Xu, Cunlian Wang, Mingju Xu, Ruihua Zhang, Baojian Liu, Dong Wei, Guohua Wang, Shufei Tian. Carnosine markedly ameliorates H9N2 swine influenza virus-induced acute lung injury. Journal of General Virology,2015,96(10):2939-2950 ( IF=3.18)

[4] Zhang RH,Ai X,Duan YJ, Xue M, He WX, Wang CL, Xu Tong*, Xu MJ , Liu BJ, Li CH, Wang ZJ, Zhang RH, Wang GH, Tian SF, Liu HF. Kaempferol ameliorates H9N2 swine influenza virus-induced acute lung injury by inactivation of TLR4/MyD88-mediated NF-κB and MAPK signaling pathways. Biomedicine & Pharmacotherapy, Volume 89, Issue null, Pages 660-672 ( IF=2.32)

[5] Rui-HuaZhang, Chun-HongLi, Wen-XiaoHe, Cun-LianWang, TongXu*, Mei-LinJin, Huan-ChunChen. Development of latex agglutination test with nucleoprotein as antigen for detection of antibodies to swine influenza virus [J]. Int Immunopharmacol, 2014, 19(2):201-205(IF=2.71).

[6] Rui-Hua Zhang, Chun-Hong Li, Cun-Lian Wang, Ming-Ju Xu, Tong Xu * , Dong Wei, Bao-Jian Liu,Guo-Hua Wang, Shu-Fei Tian. N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury [J]. Int Immunopharmacol, 2014, 22(1):1-8(IF=2.71).

[7] Xu Ming-Ju, Liu BJ, Wang CL, Wang GH, Tian Y, Wang SH, Li J, Li PY, Zhang RH, Wei D, Tian SF, Xu T*. Epigallocatechin-3-gallate inhibits TLR4 signaling through the 67-kDa laminin receptor and effectively alleviates acute lung injury induced by H9N2 swine influenza virus Int Immunopharmacol, 2017, 52:24-33(IF=2.91).

 [8] Zhang RH, Cui HY, Xu MJ , Li Kai, Chen HL , Wang CL, Wei D, Li CX, Xu Tong*. Molecular characterization and pathogenicity of swine influenza H9N2 subtype virus A/swine/HeBei/012/2008/(H9N2) [J].Acta Virol, 2011, 55(3): 219 -226 (SCI)

[9] Wei D, Huang ZH, Zhang RH, Wang CL, Xu Ming-Ju, Liu BJ, Wang GH, Xu T*.  Roles of p38 MAPK in the regulation of the inflammatory response to swine influenza virus-induced acute lung injury in mice [J]. Acta Virol, 2014, 58(3):227-333(SCI).

[10] Wei Dong, Xie Li-FenG, Wang cun-lian , Xu Ming-Ju, Zhang Rui-hua , Liu Ying, Xu Ttong*. A mouse model of swine influenza virus H9N2 infection with acute lung injury [J]. Acta Virol, 2012, 56(3):227-233(SCI).

[11] Zhang RH, He WX, Xu T*.Characterization of the complete mitochondrial genome of the king pigeon (Columba livia breed king), Mitochondrial DNA, 2015,26(3):491-2

[12] Zhang RH, Xu MJ, Wang CL, Xu T*, Wei D, Liu BJ, Wang GH, The complete mitochondrial genome of the Fancy Pigeon, Columba livia (Columbiformes: Columbidae), Mitochondrial DNA, 2015, 26(1):162-3

合作指导博士论文

[1] p38MAPK在H9N2-SIV诱导小鼠急性肺损伤中的作用.博士论文, 2013年,甘肃农业大学.

[2] 人参皂苷Rb1对H9N2-SIV诱导小鼠肺氧化应激损伤及Toll样受体4信号通路的影响.博士论文,2014年,甘肃农业大学.